Mental health is a critical issue affecting individuals and society. Even academia has not been immune to this pandemic, with growing concerns about declining mental health among students, faculty, and staff. Our research aims to investigate how the built environment can influence the body and mind and how its elements impact prolonged stress in college students. We have recently built an adaptive and flexible environment called Personal Emotional Augmented Controlled Environment (PEACE). Along with PEACE, we have developed a multi-modal bio-behavioral data acquisition platform to capture and study individuals' physiological and behavioral signals in response to multiple PEACE factors such as light, sound, and form.